5-Androstenedione CAS 571-40-4 With Best Price

Chemical Properties:

5-Androstenedione (CAS 571-40-4): Applications and Key Uses

5-Androstenedione (CAS 571-40-4), also known as 5α-Androst-1-ene-3,17-dione or Δ1-Androstenedione, is a steroidal compound with significant applications in pharmaceuticals, biochemistry, and research. Below is a detailed overview of its key application areas:  

1. Pharmaceutical Synthesis**

5-Androstenedione serves as a critical intermediate in the synthesis of steroidal hormones and related drugs. It is a precursor in the production of testosterone and other androgens, which are essential for developing therapies targeting hormonal imbalances, hypogonadism, and certain metabolic disorders. Additionally, it is utilized to synthesize derivatives like Δ1-Testosterone, a prodrug studied for its potential anabolic effects in muscle growth and recovery.  

2. Biochemical Research

As a steroidal compound, 5-Androstenedione is widely used in biochemical studies to investigate enzyme pathways, particularly those involving steroidogenesis (e.g., aromatase and 5α-reductase enzymes). Researchers employ it to explore metabolic pathways, receptor interactions, and hormonal regulation mechanisms.  

3. Sports Supplements (Controversial)

While not its primary application, 5-Androstenedione has been marketed as a dietary supplement to boost testosterone levels and enhance athletic performance. However, its use in sports is controversial due to potential health risks and regulatory restrictions in many countries.  

 4. Steroid Hormone Production

This compound plays a role in industrial steroid manufacturing, where it acts as a starting material for synthesizing corticosteroids (e.g., dexamethasone) and anti-inflammatory agents. These derivatives are vital in treating conditions like arthritis, allergies, and autoimmune diseases.  

 5. Research on Hormonal Disorders

5-Androstenedione is utilized in preclinical studies to model and understand disorders such as polycystic ovary syndrome (PCOS) and adrenal hyperplasia, where abnormal steroid metabolism is implicated.  

 Safety and Regulatory Considerations  

Although 5-Androstenedione is generally stable under controlled conditions, its handling requires adherence to safety protocols, including protective equipment and proper storage away from oxidizers. Regulatory frameworks, such as controlled substance designations in some regions, further govern its use in pharmaceuticals and supplements.  

For further details on its physicochemical properties or synthesis methods, refer to the cited sources or specialized chemical databases.